2026 MIPS Measure #491: Mismatch Repair (MMR) or Microsatellite Instability (MSI) Biomarker Testing Status
Quality ID491
eMeasure IDNone
NQF3661
High-Priority MeasureYes
Specifications
—
Measure TypeProcess
MVP IDYes (MVP ID: M1501)
Specialty
Pathology
Measure Description
Percentage of surgical pathology reports for primary colorectal, endometrial, gastroesophageal or small bowel carcinoma, biopsy or resection, that contain impression or conclusion of or recommendation for testing of mismatch repair (MMR) by immunohistochemistry (biomarkers MLH1, MSH2, MSH6, and PMS2), or microsatellite instability (MSI) by DNA-based testing status, or both.
Measure Submission Type
MIPS clinical quality measures (MIPS CQMs)